报告人：Professor Jonathan R. Nitschke
报告题目：Functional Metal-organic Structures Self-assembled from Simple Precursors
报告时间：11月26日（周三）15:00-16:00
报告地点：生物医药与先进材料研究中心报告厅
报告内容： Research in Professor Nitschke focuses on discovering and developing new ways in which simple building blocks may be induced to self-assemble into complex, functional structures. The investigations currently focus upon the self-assembly of imine bonds around metal-ion templates, bringing both covalent C=N and coordinative N→Metal bonds into being during the same overall self-assembly process. The structures thus created can rearrange in well-defined ways at both covalent and coordinative linkages. Ongoing projects include:
Container Molecules. The diamine and aldehyde shown above self-assemble with iron(II) in water to form a tetrahedral cage. This cage traps guest molecules within its cavity with high selectivity. The cage may be opened and the guest released using different triggers, one of which is a drop in pH. Applications in drug delivery are of interest, as are investigations of changes in the reactivity and behaviour of guest molecules upon encapsulation.
Functional Materials. We have recently developed means to create metal-containing conjugated polymers through self-assembly. DFT calculations carried out by Laura Gagliardi and Christopher Cramer suggest that these might conduct electricity. Studies are thus being undertaken to investigate their properties
报告人简介：Jonathan R. Nitschke (JN) is Professor at Cambridge from October 2014. His independent programme has produced peer-reviewed publications in top international journals (Nature, Science, Nature Chemistry, PNAS, Angew. Chem., JACS, Acc. Chem. Res). His expertise in the emergent field of Systems Chemistry has been recognised by an invitation to write a tutorial Q&A review, ‘Molecular networks come of age’, for Nature. His work has been highlighted in Nature, Chem. Eng. News, Chem. World, New Scientist, and featured on the front cover of Angew. Chem. He is a member of the editorial board of the Journal of Physical Organic Chemistry, the editorial advisory board of Chemical Science, the RSC’s new flagship journal, and organiser of the successful Royal Society of Chemistry Supramolecular & Macrocycles conference of December 2009. ProfessorNitschke’s awards and honours include: Corday-Morgan Prize, Dalton Transactions European/African Lectureship, European Young Chemist Award, Swiss National Science Foundation Professorship and Werner Prize.
